HIV Orange
AIDS Vaccine Basics is comprised of our popular Primer series, textbook-like chapters of about 800 words each that aim to translate the complex world of AIDS vaccine science into simple but informative language. Here you will find deftly written explanations on how different AIDS vaccine strategies work, what cells comprise the different arms of the human immune system, and how to interpret the results of AIDS vaccine trials. The page contains a searchable key that allows readers to track down Primer topics dating back to 2003.

Understanding Sequential Immunization Strategies
VAX October 2016
How are researchers using a step-wise approach to try to train the immune system to fend off HIV?
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Understanding the Rationale for the HVTN 702 Trial
VAX August 2016
What have scientists learned that helped inform the design of this pivotal AIDS vaccine study in South Africa?
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Understanding the Gut Microbiome and HIV
VAX April 2016
Why are HIV researchers interested in the bacterial and fungal environments present in the human digestive system?
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Understanding Microbicide Development
VAX January 2016
What progress is being made in the development of vaginal microbicides?
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Understanding Germinal Centers
VAX November 2015
What are scientists learning about the structures within which antibody-producing cells develop and mature?
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Understanding Ebola Vaccine Development
VAX September 2015
What are the strategies scientists are using to develop vaccines to prevent Ebola?
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Understanding the Viral Reservoir
VAX July 2015
Why is curing HIV such a daunting task?
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Understanding Community Immunity
VAX March 2015
What is herd immunity and what happens when it breaks down?
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Understanding the Importance of Striking a Balance with Vaccination
VAX January 2015
Why is it important for an AIDS vaccine to induce a balanced immune response?
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Understanding Advances in Therapeutic Vaccine Research
VAX November 2014
What recent developments are fueling research into using vaccines to treat or even cure HIV?
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Understanding the Bulk Production of Broadly Neutralizing Antibodies
VAX May 2014
How will researchers manufacture broadly neutralizing antibodies for HIV prevention and treatment studies?
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Understanding the Expanding Role for Broadly Neutralizing Antibodies
VAX March 2014
Could the same antibodies that have become the crux of vaccine research have a role in treating or even curing HIV?
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Understanding VLP Vaccines
VAX January 2014
What are virus-like particles and how are they being used in the design of AIDS vaccine candidates?
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Understanding the Role of T Follicular Helper Cells in Responding to HIV
VAX September 2013
How does this subset of cells differ from other T cells, where do you find them, and how are they important to AIDS vaccine and cure research?
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Understanding the P5 Partnership
VAX July 2013
How is this research collaboration advancing the development of a safe and effective AIDS vaccine?
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Understanding Test-of-Concept Trials
Why are Phase IIb trials an important step in evaluating AIDS vaccine candidates?
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Understanding Risk-Reduction Counseling
Why is risk-reduction counseling an important part of AIDS vaccine trials?
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Understanding How a Vaccine May be Designed to Induce Broadly Neutralizing Antibodies
VAX May 2013
Could recent breakthroughs in research be applied to make broadly effective vaccines against HIV?
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Understanding Therapeutic Vaccination
VAX March 2013
What is therapeutic vaccination and how are scientists using it today to develop new strategies against HIV?
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Understanding How Researchers are Tackling HIV's Genetic Variability
VAX January 2013
What new startegies are scientists developing to design broadly effective vaccines against HIV?
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